Pharmacological interventions for bacterial prostatitis. Traducere "prostatitis" în română
Category I is acute bacterial prostatitis. It is an acute prostatic infection with a uropathogen, often with systemic symptoms of fever, chills and hypotension. The treatment hinges on antimicrobials and drainage of the bladder because the inflamed prostate may block urinary flow.
Category II prostatitis is called pharmacological interventions for bacterial prostatitis bacterial prostatitis. It is characterized by recurrent episodes of documented urinary tract infections with the same uropathogen and causes pelvic pain, urinary symptoms and ejaculatory pain.
This entity is, by definition, asymptomatic and is often diagnosed incidentally during the evaluation of infertility or prostate cancer.
The clinical significance of category IV prostatitis is unknown and it is often left untreated. It is characterized by pelvic pain for more than 3 of the previous 6 months, urinary symptoms and painful ejaculation, without documented urinary tract infections from uropathogens.
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The diagnosis relies on separating this entity from chronic bacterial prostatitis. If there is no history of documented urinary tract infections with a urinary tract pathogen, then cultures should be taken when patients are symptomatic.
Prostatic localization cultures, called the Meares-Stamey 4 glass test, would identify the prostate as the source for a urinary tract infection in chronic bacterial prostatitis.
For healthcare providers, the focus of therapy is symptomatic relief. Second-line pharmacotherapy involves anti-inflammatory agents for pain symptoms and alpha-adrenergic receptor antagonists alpha-blockers for urinary symptoms. Third-line agents include 5alpha-reductase inhibitors, glycosaminoglycans, quercetin, cernilton CN and saw palmetto.
For treatment refractory patients, surgical interventions can be offered. Transurethral microwave therapy to ablate prostatic tissue has shown some promise. The treatment algorithm provided in this review involves a 4- to 6-week course of antibacterials, which may be repeated if the initial course provides relief. Pain and urinary symptoms can be ameliorated with anti-inflammatories and alpha-blockers.
If the relief is not significant, then patients should be referred for biofeedback. Minimally invasive surgical options should be reserved for treatment-refractory patients.
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- Pavel Banov - Академия Google